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2 Results 2.1 Pharmacokinetic studies of BPC157 in rats The effective dose of BPC157 for the treatment of various injuries in mice, rats, and rabbits ranges from 6 to 50 g/kg ( The mean (+SD) plasma concentration of BPC157 versus time curves following administration of various BPC157 doses in rats are shown in Figures 1AC, and the corresponding pharmacokinetic parameters are presented in Tables 1Tables 3

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doi:10.1038/nature03000 Sosne G, Kleinman HK, Springs C, Gross RH, Sung J, Kang S

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Depending on the treatment groups, an unpaired t test or one-way or two-way ANOVA with a Holmdk multiple comparisons test was applied