Splitting the daily total across two injections is common in twice-daily reference schedules
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doi:10.1016/j.biochi.2016.02.012 [PubMed] [Elsevier] Hanna M, Jaqua E, Nguyen V, Clay J
Research uses 200 to 800 mcg per day, with 10 mcg/kg as the common animal reference, which scales to roughly 200 to 500 mcg/day in humans
becomes particularly relevant, and the answer truly varies depending on a few key factors: The Underlying Cause of Deficiency: The Underlying Cause of Deficiency: Pernicious Anaemia/Malabsorption: For those with an inability to absorb B12 orally (like in pernicious anaemia), injections are typically a lifelong treatment
Vitamin B12 is an essential nutrient that helps support energy and red blood cell production