The Golden Rule: Consistency over everything
More importantly, the NO synthase blocker L-NAME can reverse these effects of AKT and p38/MAPK signaling pathways induced by BPC 157, but cause no changes on ERK/MAPK
Research in preclinical models has explored its role in NNMT inhibition, NAD+ metabolism, and cellular energetics (pmc.ncbi.nlm.nih.gov, pubmed.ncbi.nlm.nih.gov)
it is naturally occurring, nontoxic, and is active at a very low nanomolar concentration.11 Another piece of research described GHK-Cu as a safe, inexpensive, extensively studied compound.3 These conclusions primarily apply to topical GHK-Cu, but even with injectables, the lack of serious adverse events in animal subjects points to a general tolerability regardless of the route of administration
A thorough personal and family history, especially regarding cancer and diabetes, is essential before any GH-axis stimulant is considered
Injectable or topical directly to the area (depending on wound type)