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Dose frequency should relate to the severity of the deficiency

Document whether appetite suppression diminished, whether the same dose produces fewer gastrointestinal effects than previously, and whether metabolic parameters began deteriorating

Proper administration requires qualified professionals ensuring sterile technique, appropriate dosing, and readiness for any reactions

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10.1111/j.1462-5822.2011.01682.x Cell

Identification of molecular mechanisms related to nonthyroidal illness syndrome in skeletal muscle and adipose tissue from patients with septic shock