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ABG/VBG (alkalemia may be problematic and require treatment)

It is discrete, hyperpigmented macules or patches on genitalia and histopathologically, the number of melanocytes is normal, but there is increased basal layer hyperpigmentation with lack of melanocytic hyperplasia (5)

A portion of LC patients have symptoms similar to myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), which results in a substantial reduction in their quality of life

Early proof-of-concept and phase 2 studies suggested that tirzepatide can improve both markers of beta cell function and insulin sensitivity compared with selective GLP-1 RA therapy [9, 10]

For example, CD36 (52), one of the fatty acid translocases (FAT), contributes to the growth and distant metastasis of ovarian cancer cells

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