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A gain of 12 pounds per week is expected as your body resets

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The evidence supports their safety in psychiatric populations

Long-term use beyond the recommended period increases the risk of physical and psychological dependence

Patients on semaglutide who took a weekly dose of 2.4 mg for 68 weeks, or roughly 15 months, dropped an average of 35 pounds, or 15% of their body weight, compared to 2.4% for the placebo group