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Jennings BL, Moore JA, Pingili AK, Estes AM, Fang XR, Kanu A, et al

Indeed, benzoquinones can covalently react with diverse macromolecules whereas hydroquinones, conjugated or not with glutathione, are prone to auto-oxidation forming reactive oxygen species

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P-GLYCOPROTEIN A protein localized to the cell membrane that actively pumps many drugs out of the cell