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Although a direct comparison of high-dose oral allulose with injectable GLP-1 drugs remains to be done, the preliminary data suggests that adding allulose to your diet (or better yet including it in food products that are easily integrated into any diet) may provide a more natural alternative to achieving long-term weight loss than to use of chemically modified hormones (i.e., GLP-1 drugs) with their significant side effects

As stated in section XV.B.1

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The condition is becoming more common as populations age and levels of obesity and sedentary lifestyles rise

The high flexibility and length of the -glutamyl bond formed by glutamic acid and cysteine in GSH contribute to the instability of its interactions with the loop regions