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These receptor configurations are commonly referred to as AMY1, AMY2, and AMY3 receptors and are distributed throughout tissues involved in nutrient sensing, gastrointestinal physiology, and central nervous system signalling

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PMCID: PMC5392015

Rotate sites to prevent lipohypertrophy (lumps at injection sites)

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These results are roughly in line with what Lilly has demonstrated for tirzepatide (22.5% and 20.9% respectively at 72 weeks), but fall short of the 25% bar for efficacy many investors were anticipating, BMO Capital Markets analysts wrote in a note to investors