Research & Evidence Current evidence for 5-Amino-1MQ centers on preclinical (animal and cell) research on NNMT inhibition, with limited human data to date
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Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)
It acts as a mitochondrial protective agent, stabilizing mitochondrial structure, enhancing oxidative phosphorylation, reducing production of reactive oxygen species (ROS), and mitigating cellular damage in diverse models of mitochondrial dysfunction
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Weghorst, Buitelaar, and Pelzer, 2024)