Until we have larger, more definitive studies, the safest approach is still to stop GLP-1 medications before trying to conceive. The findings, however, are exactly the kind of data we need to justify properly designed prospective trials, says Lora Shahine, MD, a reproductive endocrinologist and obstetrician-gynecologist at PNWF IVY Fertility Center in Bellevue, Washington, and host of the Brave and Curious podcast
Non-GLP-1 weight loss medications offer alternatives for patients unable to tolerate GLP-1-related gastrointestinal effects
GLP-1 therapies work best when combined with lifestyle modifications
Expect smaller weight loss than in trials
Treat any advert for GLP-1 patches with caution , especially if it's being promoted by an influencer on social media or making bold claims about weight loss results
Figure 6