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IGF-1R activation initiates insulin receptor substrate (IRS-1/2) phosphorylation PI3K-p85/p110 recruitment PIP3 generation PDK1-mediated Akt (Ser473 via mTORC2

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Proteomics 13 (10-11), 16601666

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The Data is a part of the AHFS Drug Information

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The current study identified Day 30 of iHLOs as the optimal developmental stages that can be used for pharmacological and toxicological research

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In some embodiments, the otoprotectant is Potassium Thiosulfate

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