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10.1586/1744666X.2014.942288 145

*Correspondence: Ethan Will Taylor [email protected] This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This effect is primarily mediated by an increase in the phosphorylation of insulin receptor substrate 1 (IRS1) and a concomitant inhibition of Akt phosphorylation, a crucial component of the insulin signaling pathway

Others report that food occupies less emotional and logistical space, leaving more attention for work, family, or ordinary life

Patients should be educated on recognizing and managing hypoglycemic episodes

Pes GM, Parodi G, Dore MP