On Bone Repair Thymosin Beta-4 research has demonstrated effects on osteoblast differentiation and activity, suggesting a role in the mineralization phase of bone repair
Beyond simple actin sequestration, Bock-Marquette and colleagues reported in Nature (2004) that T4 activates integrin-linked kinase and Akt, promoting cardiomyocyte and epicardial cell migration and survival in mouse cardiac injury models, which established a signalling role separate from cytoskeletal buffering
In angiogenesis research, BPC-157 has been shown to stimulate expression of vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) in cell cultures
The combination uses therapeutic but conservative doses of each component, and the synergistic effects actually allow for lower individual peptide amounts than if using them separately
Understanding Peptides Peptides are short chains of amino acids that function throughout the body in a number of capacities, including in the reproductive system
Emerging Peptide Therapeutics and Future Directions Pipeline Developments The peptide therapeutics pipeline continues to expand, with numerous candidates in various stages of clinical development