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In animal experiments, it has been demonstrated that the endogenous GLP-1 receptor system is involved in the control of fluid intake and that, unlike food-generated stimuli, both endogenous GLP-1 and exogenous GLP-1 Ras inhibit fluid intake by activating the central nervous system GLP-1 receptor ( In previous real-world studies of GLP-1 RAs-induced hypoglycemia, lixisenatide showed the strongest association (Figure 2)

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However, if you have a sensitive stomach, taking it with a small amount of food is perfectly fine and can help prevent mild digestive discomfort

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