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In order to monitor and prevent the formation of diketopiperazines (DKP), we simultaneously synthesized the sequences using two different types of resin functionalization, i.e., Wang and 2-chlorotrityl resin, expecting differences between the two resins due to the steric hindrance of the trityl group on trityl resin that should prevent the formation of diketopiperazine better than Wang resin

Rodriguez CI, Castro-Perez E, Prabhakar K, Block L, Longley BJ, Wisinski JA, et al

In the case of children, it is recommended to consult with a healthcare professional before using it

doi:10.1159/000430199 101