Cognitive Support Higher NAD levels activate sirtuins 10 (SIRT1, SIRT3), which protect brain cells by reducing oxidative stress, supporting DNA repair, and improving mitochondrial health
It makes sitting a nightmare, standing a chore, and finding a comfortable position to sleep a seemingly impossible task
Long-term optimization As your body responds, we refine your plan to help you maintain energy, metabolism, cognition and overall wellness
the original rodent study used 5 mg/kg, which when scaled allometrically to human equivalents suggests doses in the 5-10 mg range for a 70 kg adult, though allometric scaling from mice to humans is an imprecise science
Research links it to signaling involved in skin remodeling, antioxidant defense, and repair processes, which is why it is used for visible aging concerns, barrier support, and scalp-focused routines
There are a few exceptions