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Available inducers (e.g., erastin, RSL3, elesclomol) often suffer from poor pharmacokinetics, limited tumor selectivity, and narrow therapeutic windows, leading to potential off-target toxicity

Most people tolerate the medications well

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Determine possible causes of fatigue, such as last physical illness, pain, emotional stress, depression, side effects of medication, anemia, sleep disorders, imbalanced nutritional intake, and extended responsibilities and demands at home or work

do not stop prescribed medicines without advice

In cases of neuropathy, disc injury, or systemic inflammation, peptides help restore nerve network efficiency