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Cystine starvation has been shown to impede TNBC growth, which affects stem cell properties and chemotherapy resistance in TNBC (27), thereby promoting TNBC cell ferroptosis through activation of the general control nonderepessible 2-eukaryotic translation initiation factor 2 subunit 1-activating transcription factor 4-CHAC1 pathway through the specific cytosolic GSH degradation enzyme CHAC1 (28)

For someone going through the full titration from 2.5mg to 15mg, the 30mg vial format is often the most practical choice

At 5 mg/mL: 0.25 mg = 5 units = 0.05 mL 0.5 mg = 10 units = 0.1 mL 1.0 mg = 20 units = 0.2 mL 1.7 mg = 34 units = 0.34 mL 2.0 mg = 40 units = 0.4 mL 2.4 mg = 48 units = 0.48 mL The lower volumes can be hard to see in a 1 mL syringe

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Tlaskalov-Hogenov et al