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Other common effects include fatigue (10-15%), headache (10-15%), and increased heart rate (5-10 bpm average increase)

High levels of IGF-1, the opposite end of the U-shaped curve, are most commonly the result of excess GH production

The most common side effects reported are minor temporary injection site redness or mild headache in some individuals

The yeast Candida albicans can synthesise carnitine, and while it is not clear whether this is possible in bacteria, they can acquire it from the environment or from metabolic precursors, as it is used in protection against environmental stresses in some species

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(More information) It is not yet clear whether supplementation with B vitamins, antioxidants, or omega-3 fatty acids protects against age-related cognitive decline