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Cells exposed to high concentrations of copper for an extended period have a larger volume and more mitochondria to ensure normal osmoregulatority [149]

doi: 10.1016/j.intimp.2020.107272 145 SimpsonMFrisbeeAKumarPSchwanCAktoriesKPetriWA

USA 113 , 88438848 (2016)

Ongoing Knowledge Gaps Researchers frequently cite the need for more data on: long-term biological effects comparative efficacy vs single-peptide models combined-use safety profiles dosing and timing variables applicability across different tissues or injury types reproducibility of findings in larger or more diverse models These gaps highlight the early-stage nature of the evidence base

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