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A meta-analysis of 12 randomized controlled trials (n = 17,996) further confirmed these renoprotective effects, with agents structurally closer to endogenous human GLP-1, such as semaglutide, showing the strongest benefit (RR = 0.78, 95% CI: 0.710.85) ( 3.4 Hepatic protection In clinical practice, semaglutide has demonstrated notable efficacy in resolving NASH without aggravating hepatic fibrosis

Vit-D deficiency is also associated with an increase in thrombotic episodes, frequently reported in COVID-19 695

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[8] In such patients, MB should be avoided or used only with close monitoring, and at minimum, dosage reduction is advised

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