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Results Drug-induced tendinopathy in spontaneous reporting systems First, we investigated the association between the use of a particular drug and the incidence of tendinopathy in FAERS, CVARD, and JADER using a disproportionality analysis by calculating each ROR and its Z score
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Interestingly, although APAP-induced liver damage was primarily due to its biotransformation to toxic metabolites by CYP4502E1, MEL had no effect on its expression
Additionally, HEB, derived from normal human astrocytes, was also obtained from ATCC
Accumulation of lipid peroxides drives ferroptosis Polyunsaturated fatty acids (PUFAs) containing bis -allylic carbons are highly susceptible to lipid peroxidation [37], and recent findings suggest that a wide range of PUFAs may be involved in the ferroptosis pathway [15]