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Prog Neurobiol 81:89131

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While this is the licensed indication, it's important to note that NICE guidance (TA875) recommends more specific criteria for NHS use: typically for people with a BMI 35 kg/m (lower thresholds may apply for some ethnic groups) with at least one weight-related comorbidity, prescribed within specialist weight management services, and limited to a maximum treatment duration of 2 years

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GO analysis showed that the DEPs were primarily enriched in biological processes associated with 'PPAR signaling pathway', 'ferroptosis' and 'pentose phosphate pathway' (Fig

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