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The American Diabetes Association (ADA) Standards of Care and American College of Physicians (ACP) guidelines support the use of GLP-1 receptor agonists, including dual agonists like tirzepatide, as effective options for glycemic control and weight management

Given the increasing interest in the potential use of incretins in cardiovascular diseases, conducting randomized controlled trials in this direction is warranted

2017;20(2):177-190e4

Development of cagrilintide, a long-acting amylin analogue

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In October 2024 the UK government, for example, estimated that obesity cost the UK health service more than 11 billion each year (UK Government)