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It is important to emphasize that oral semaglutide is initiated at a sub-therapeutic dose (3 mg daily) for the first 30 days to improve gastrointestinal tolerability

Cross-trial comparisons remain observational, not head-to-head

Protecting Innovation: The development of novel peptide formulations and patent protections ensures access to innovative therapies

2 To guide these conversations effectively, providers may benefit from grounding treatment recommendations in a continuum-of-care approach, one that reflects obesity as a chronic condition requiring ongoing, evolving support and acknowledges the potential out-of-pocket costs that can influence follow-through over time

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