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Racemic mixture versus R-lipoic acid only R -lipoic acid is the isomer that is synthesized by plants and animals and functions as a cofactor for mitochondrial enzymes in its protein-bound form (see Biological Activities)

Both Akkermansia studies used laboratory conditions - animal models and cell cultures - rather than human clinical trials evaluating oral supplementation at this dosage

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GLP-1 release from stomach and colon fragments incubated ex vivo Stomachs and colons of ND lean or HFD obese rats were collected after euthanasia, washed to remove the debris and then cut into small pieces