GLP-1RAs@NPs-WYRGRL inhibited ferroptosis in chondrocytes by suppressing the cGAS-STING signaling pathway and promoted macrophage polarization toward the M2 phenotype In this study, western blotting was first conducted to investigate the ability of GLP-1RAs@NPs-WYRGRL to inhibit ferroptosis in chondrocytes
Narring, Genve (Mdecine de ladolescence)
They cant cure diabetes disease properly but help to manage and minimize the risk of complications
Although current evidence supports broad applicability across BMI, diabetes status, and fibrosis stages F2-F3, subgroup analyses suggest attenuated responses in non-obese patients and in certain ethnic groups (Hispanic patients in ESSENCE), emphasizing the need for precision medicine approaches incorporating anthropometric, genetic (e.g., PNPLA3, HSD17B13), and metabolic profiling
Acta Paediatr 1996, 85: 446-449
Qi F, Qian S, Zhang S, Zhang Z