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In this role, glutathione makes sure that toxins like heavy metals, organic toxins, and even the actual byproducts of the process of creating energy by the mitochondria themselves (oxidative byproducts or free radicals) don't damage the mitochondria

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Wozniacka A, Sysa-Jedrzejowska A, Adamus J, Gebicki J

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"The role of NAC in glutathione synthesis." Journal of Hepatology , 2019

Hyperglycemia enhances the generation of ROS and RNS that impair antioxidant power and cause oxidative damage in human erythrocytes