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This association remained statistically significant in the analysis of adjusted ORs (OR, 2.35

This balanced approach ensures that while hyperpigmentation fades, the skin maintains its essential ability to protect itself from environmental damage

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They showed that semaglutide enhanced histological parameters of fibrosis and inflammation while decreasing hepatic expression of genes associated with fibrotic and inflammatory cascade: through proteomic profiling of serum from MASH patients treated with semaglutide, they detected 72 proteins linked to disease resolution and validated these findings in preclinical mouse models and an independent patient cohort [28]

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