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ADDITIONAL INFORMATION SKU: MNV800 EAN: 8410885077660 Food supplements should not be used as a substitute for a balanced nutrition

Inositols in insulin signaling and glucose metabolism

Oral administration creates slower absorption with sustained but lower peak concentrations due to first-pass metabolism, which may reduce the need for daily dosing as the compound remains bioavailable for extended periods

doi: 10.1037/a0029524 61 ZhuLLBlairHCaoJYuenTLatifRGuoLet al

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In T2D patients (n = 25, age 2565), consumption of 1 g L-citrulline twice a day for 4 weeks reduces the T2D-induced increase in arginase activity and increases plasma nitrites, effects corroborated by improvement of ACh-induced relaxation in ex vivo mouse aortic rings incubated (24-h) in low or high glucose-containing media and increases in NO production in ECs treated with high glucose (Shatanawi et al., 2020)