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Merck's MK-0893, Lilly's LY2409021, and Pfizer's PF-06291874 all reached Phase 2 and all failed - transaminase elevations, LDL increases, weight gain
JCI Insight 5 , e140532 (2020)
The side effects are similar to semaglutide GLP-1, primarily gastrointestinal discomfort
Blackshaw, L
Compounded semaglutide is not FDA-approved, has not undergone FDA review for safety or effectiveness, and is not the same as, nor equivalent to, Ozempic or Wegovy
In fact, there are several evidence-based weight loss treatments available right now, many with strong clinical data and real-world use behind them
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