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Considering that genegene interactions may contribute to inter-individual variation in complex traits 41,42 , we tested whether epistatic interactions for SNP pairs can contribute to regulating Hg body retention and nephrotoxicity

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4.2 GSH/GSSG Imbalance in Aging and Neurodegenerative Disease Because the brain has high energy demand, abundant oxidizable lipids, and strong dependence on mitochondrial function, glutathione metabolism is frequently studied in aging and neurodegeneration