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Abstract Ligand-gated ion channels transduce chemical signals into electrical impulses by opening a transmembrane pore in response to binding one or more neurotransmitter molecules

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Probenecid can also cause a rash but seems less likely than allopurinol to cause a very severe hypersensitivity reaction

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If you are not going to use the full reconstituted vial within 28 days, consider whether your protocol requires you to reconstitute the full vial at once, or whether you can keep the lyophilised remainder sealed and reconstitute in smaller portions as needed