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8.5 Extension to dual, triple-agonist and amylin-based co-agonist therapies The emergence of dual and multi-agonist therapies, such as the GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide, raises important questions regarding the generalisability of the proposed framework

Increased catabolism of amino acids leads to the release of the amine group from amino acids whose carbon skeletons are used to replete intermediates of energy metabolism

A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation

LefflerDAKellyCPAbdallahHZColatrellaAMHarrisLALeonFet al

If Kaiser's formulary committee says no, your options within the system are limited