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These channels are typically formed by the assembly of 15 monomers of GspD (e.g., GspD Ecol 15mer PDB ID code 5WQ7), or 12 to 14 (in some cases up to 19 15 ) monomers of PilQ (e.g., PilQ Mxan 12mer PDB ID code 3JC9

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Based on results of SPR, the PV2-PV3 fusion protein demonstrated a kD value of 63.5 nM, while the PV2-S71 + PV3-N77 combination exhibited a significantly enhanced binding affinity with a kD of 6.34 nM

Prabakaran S, Swatton JE, Ryan MM, Huffaker SJ, Huang JT, Griffin JL et al

Design, synthesis, and structural characterization of thioflavones and thioflavonols as potential tyrosinase inhibitors: In vitro and in silico studies

Taking L-lysine is considered safe