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Journal of Cellular Physiology 206, 655-663CrossRefGoogle ScholarPubMed 57Schipper, H.M

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Hepatic overexpression of SIRT6 inhibits intestinal cholesterol and fat absorption and reduces very low-density lipoprotein secretion, providing protection against steatohepatitis and atherosclerosis induced by a Western diet in Ldlr / mice [14]

Long-term deficiency can damage the protective myelin around nerves, and if it is not addressed, some of that damage can become permanent, causing numbness, pain, and balance problems

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