En los pocos estudios publicados, no se han reportado efectos adversos graves, pero el nmero de pacientes es muy bajo y no hay datos de seguridad a largo plazo
and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals
All patients received SOC as determined by the investigators
Mashour GA, Drissel SN, Frahm S, Farassati F, Martuza RL, Mautner VF, et al
Vitamin B-12 is essential for the creation of DNA and the metabolism of cells, and deficiencies in these can lead to anemia, fatigue, muscle weakness, digestive issues, nerve damage, and mood swings
This may reflect underlying differences in T2D severity or clinical management between the treatment groups
