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J Biol Chem 284:19902000 [DOI] [PMC free article] [PubMed] [Google Scholar] Zheng H, Chu J, Qiu Y, Loh HH, Law PY
Blocking metallothionein-2 expression by copper-doped carbon dots induces cellular antioxidant system collapse for antitumor therapy
Most patients notice initial hydration and surface smoothness within 12 weeks
Mol Brain Res 15: 207215
Since it lasts only for a limited time, this process needs to be repeated for skin whitening, as the practitioner suggests
In contrast, desensitization usually refers to molecular changes at the level of receptor signaling and can be homologou s (reduced effects restricted to agonists acting through a specific receptor) or heterologous (reduced effects of agonists acting at other receptors that share a component of the signaling cascade, Lefkowitz et al., 1983)
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