Thiamine does not allow the expression of the Bcl-2 family of pro-apoptotic proteins, caspase-3 activation, and poly-(ADP-ribose) polymerase (PARP) cleavage
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To support safe prescribing, providers can reference trusted resources like the CDC diabetes guidelines
Some doses are also available in vials
Cases of vitamin B deficiency have been reported, including Wernickes encephalopathy, a neurological condition caused by thiamine deficiency that begins with confusion and can progress to irreversible brain damage if not detected