The observed dynamics of these metabolites in response to supplementation and disease states offer new insights into redox biology and metabolism
Overexpression of GSTP1 resulted in a two-fold increase in GSH-conjugation of the QIs, attenuated QI-induced cytotoxicity especially under GSH-depletion condition, abolished QIs-induced apoptosis but did not significantly inhibit the activation of the ER stress response
Our Vitamin B12 shot delivers a potent dose of this essential nutrient directly into your bloodstream, bypassing the digestive system and ensuring maximum absorption
Researchers have found that only around 40% of people are able to produce urolithin A due to differences in individual gut microbiomes.6 Fortunately, other studies have found that the remaining 60% of people can overcome that limitation through supplementation.12 Most of the potential benefits of urolithin A are attributed to the compounds effects on mitophagy.7 This is when your body cleans up damaged or excess mitochondria,8 then replaces them with new, healthy ones to maintain mitochondrial homeostasis.14 As you age, the rate and effectiveness of the mitophagy process decrease
It hits gene expression controls, including potential histone protein binding and regulation of specific DNA regions
Enhancing tissue repair after intense physical activity or injury
