Whether youre new to GLP-1s, been on them for a while, or are pursuing a different weight loss path, here are some research-backed, easy-to-implement hacks to protect your brain and body: Lifestyle Tips Exercise: Regular strength training preserves muscle mass and metabolism, supporting brain health and maintaining muscle that is commonly lost during GLP-1 use
Use stool softeners or osmotic laxatives when needed, after checking with your clinician
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Cannabis While no pre-clinical or mechanistic study has considered GLP-1RAs for cannabis misuse so far, a large epidemiological investigation has recently noted an association between semaglutide use and fewer cannabis-use disorders in both patients with T2DM ( N = 596,045) and patients with obesity ( N = 85,223) over a 1-year follow-up 114
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Those who dont, quit during the hardest weeks