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During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]

glutathione , not only protects our cells from oxidative damage but is also key for proper thyroid function

10.1046/j.1468-3083.2003.00641.x [DOI] [PubMed] [Google Scholar] 7.Carboni I, De Felice C, De Simoni I, Soda R, Chimenti S

At the molecular level, BMAL1 and CLOCK form heterodimers (CLOCK::BMAL1) that regulate transcription of downstream genes by binding to E-boxes, D-boxes, and Rev-erb/ROR response elements (34)