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Even though Carolines primary presentation was thyroid, digestion was an ongoing theme, and much of the focus throughout was on gut health

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BMJ 386: e086886

12 From a safety perspective, berberine was generally associated with mild adverse effects such as constipation, flatulence, nausea, headache, and transaminase elevation, with no serious adverse events reported in the reviewed trials

The insulinotropic and glucagon-suppressing effects of GLP-1 agonists directly address these goals, making them an established component of diabetes treatment algorithms

Angela Fitch, past president of the Obesity Medicine Association, told Hunterbrook she expected the GLP-1 shortage to stretch indefinitely