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Current pharmacological research models suggest Retatrutide should be strictly excluded in subjects with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Without adequate glycine, collagen production slows

This distinction makes mazdutide a unique peptide, potentially filling gaps for patients who respond less to GIP-based therapies

[PubMed] Maquart FX, et al

So far, the FDA has not found strong evidence that GLP-1 drugs cause major mental health issues