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Sirtuins at the crossroads between mitochondrial quality control and neurodegenerative diseases: structure, regulation, modifications, and modulators
Neurosci Lett 165(12):208210 Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, OCallaghan JP (2002) Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinsons disease
clinical use requires regular liver/lipid monitoring and patient education against high doses or unsupervised concentrated extracts
Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate
The effects are sustained, lasting at least six days in healthy adults