This lack of bioavailability means that even if you take a high-dose pill every day, you might not see the changes in your skin that you expect
Contrary to these results with NAC, a methionineenriched diet impaired endothelium-dependent vasodilation in WKY control rats, consistent with the increase in blood pressure seen in these animals, indicating impaired bioavailability of NO (35)
Why it matters: In tissue and cellular research, impurities can act as confounding variables that alter inflammatory or repair responses
Note that the cycle for tissue regeneration, healing, and repair is conditional: its a therapeutic goal with a defined end point, so you can discontinue use once youve reached it
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doi: 10.1098/rspb.2003.2511 19 QuintinJSaeedSMartensJHAGiamarellos-BourboulisEJIfrimDCLogieCet al