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The cagrilintide with tirzepatide combination (without semaglutide) is a different consideration that some researchers explore, but it remains untested in clinical trials

Fan W, Liu T, Chen W, Hammad S, Longerich T, Hausser I, Fu Y, Li N, He Y, Liu C, Zhang Y, Lian Q, Zhao X, Yan C, Li L, Yi C, Ling Z, Ma L, Zhao X, Xu H, Wang P, Cong M, You H, Liu Z, Wang Y, Chen J, Li D, Hui L, Dooley S, Hou J, Jia J, Sun B

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Notably, this group also determined that one day treatment at 15 the therapeutic dose or a 14 day treatment of 8 the therapeutic dose, all hematology testing was normal and therefore deemed safe

Some people may experience mild discomfort or irritation at the site of insertion