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Cytoprotection and Anti-Inflammation It reduces pro-inflammatory cytokines (e.g., TNF-, IL-6) and oxidative stress, protecting tissues from chronic inflammatory damage

The MAPK and Akt inhibitors, UO126 and Akt inhibitor VIII respectively, were used to determine to what extent, if any, activation of their targets is required for Dihexa-mediated protection

Grover K, Koblova A, Pezacki AT, Chang CJ, New EJ

Some people try to eyeball it, they figure "close enough" works, but it doesn't

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