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Both are used in medically supervised wellness programs

Valproate competes with phenytoin for binding to albumin, which increases the free level of phenytoin

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Microbial/infection Many specialists have considered IC/PBS to possibly have an infectious origin (bacterial, viral, or fungal) because microorganisms like Helicobacter pylori have been found in association with the condition, which draws parallels to chronic gastritis (Atu et al., 2004